Download e-book for kindle: Chemistry and Molecular Aspects of Drug Design and Action by E. A. Rekka,P. N. Kourounakis

By E. A. Rekka,P. N. Kourounakis

ISBN-10: 0849390060

ISBN-13: 9780849390067

An ever-increasing call for for higher medicines, increased safeguard criteria, and fiscal issues have all ended in a dramatic paradigm shift within the method that medications are being chanced on and built. often called rational drug layout, this modern procedure is outlined via 3 major steps: the invention of lead compounds, surgical manipulation to increase pharmacophores, and additional optimization to supply the simplest compounds.

Chemistry and Molecular elements of Drug layout and Action brings jointly a magnificent selection of world-renowned pharmacochemistry scientists who're presently defining the emergence of rational drug layout. supplying perception from their very own really good examine, those pioneers spotlight the range of methods being hired during this box, together with those who begin via contemplating both molecular mechanisms of drug motion, or the metabolizing enzyme motion taking place within the constitution of a drug molecule. one other process they discover is person who starts off from the pathobiochemistry and pathophysiology of goal illnesses. moreover, the booklet additionally considers drug improvement that uses already built compounds saved in facts banks.

Divided into 5 elements, every one devoted to numerous points of the classical medicinal chemistry strategy, the textual content makes it effortless for readers to target a box of particular curiosity.

  • Chemical, Biochemical, and organic elements of Pathophysiological Conditions
  • Classical Medicinal Chemistry
  • Drug layout, Chemical and Molecular points of Drug Action
  • Drug Xenobiotic Metabolism
  • Physical natural and Theoretical Medicinal Chemistry
  • While every one part will be studied independently, the mixed fabric during this quantity offers the main accomplished assessment on hand on rational drug layout. This paintings is a useful source either for these coming into the sphere, in addition to these researchers seeking to construct on present progress.

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    Chemistry and Molecular Aspects of Drug Design and Action by E. A. Rekka,P. N. Kourounakis

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